DPCstruct | MC46553

Metacluster Properties and Pfam Annotations

Number of structural domains112
Mean domain length (aa)184 ± 35 aa
Standard deviation of domain lengths35.03
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score87.97
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)24.57
Pfam Score87.21
Assigned Pfam label(s) CL0063- CL0667

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7C2L4S0 15-210 PGVPEGAITRRHILHDHEREDGLAGFISIIGGKITPYRHLAEEVVTLACRKLRLERRARPKERFEPLPGGVPFPPREVEEMAGALGV…
A0A6J4WYU0 2-138 AEDCVGHAATLAGLEAKACVTKRLNIHGYHKSPQKFGSLAIYGSDAPAIQDLLRADTLRQKLIHPALPALCGEVVWAVRFEAARTID…
W1NIE1 298-501 None
A0A1I8IQQ7 198-411 None
E9GAW1 53-263 None
A0A259K546 1-168 None
A0A1B0C2A1 1-120 None
A0A1Q7D511 2-156 None
A0A7S4URR5 8-262 None
A0A7V3GU20 37-258 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.