DPCstruct | MC46551

Metacluster Properties and Pfam Annotations

Number of structural domains450
Mean domain length (aa)273 ± 63 aa
Standard deviation of domain lengths63.45
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score84.21
Mean fraction of residues predicted as intrinsically disordered0.35
Mean length-normalized TM-Score0.38
Mean intra-cluster local Distance Difference Test score0.55
Mean intra-cluster sequence similarity (%)15.69
Pfam Score85.72
Assigned Pfam label(s) CL0023- CL0322- CL0181- CL0270- CL0187

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7V8XYY6 322-635 None
A0A1G2ZXL0 262-519 None
A0A3A0DQ42 4-542 None
A0A7Y2AHV8 374-586 None
D6D0Z2 3-217 None
A0A0S2ETQ9 94-458 None
A0A137S9S9 416-772 None
A0A1V5E9G6 19-245 None
A0A812IYN3 876-1214 None
A0A2W4QPP8 112-463 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.