DPCstruct | MC46551

Metacluster Properties and Pfam Annotations

Number of structural domains450
Mean domain length (aa)273 ± 63 aa
Standard deviation of domain lengths63.45
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score84.21
Mean fraction of residues predicted as intrinsically disordered0.35
Mean length-normalized TM-Score0.38
Mean intra-cluster local Distance Difference Test score0.55
Mean intra-cluster sequence similarity (%)15.69
Pfam Score85.72
Assigned Pfam label(s) CL0023- CL0322- CL0181- CL0270- CL0187

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5C7RC27 43-338 None
A0A3M1A848 196-511 None
A0A2X7EZH2 11-243 None
A0A7C4I7L4 191-361 None
A0A090RV06 27-356 None
A0A6N8WNC4 36-374 None
A0A2T4YWB1 164-490 None
A0A2N5IXM6 13-215 None
A0A0K8NVS1 4-224 None
A0A202DSD7 50-387 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.