DPCstruct | MC46526

Metacluster Properties and Pfam Annotations

Number of structural domains53
Mean domain length (aa)121 ± 22 aa
Standard deviation of domain lengths21.80
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score80.50
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)30.05
Pfam Score92.49
Assigned Pfam label(s) PF12338- PF00101

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0M0W7T0 1-111 MQVWPPINKKKYETLSYLPDLSQEQLLSEVEYLLKNGWVPCLEFETEHGFVYRENNKSPGYYDGRYWTMWKLPMFGCTDATQVLAEV…
A0A0E0MLJ3 98-230 NGGRIRCMQVWPIEGIKKFETLSYLPPLTVEDLLKQIEYLLRSKWVPCLEFSKVGFVYRENHRSPGYYDGRYWTMWKLPMFGCSDAT…
A0A0A2AQ53 1-88 None
A0A7S0GM48 71-211 None
A0A4S4EY92 12-146 None
A0A835AHA5 210-349 None
Q39749 21-171 None
A0A5N6PM22 368-482 None
A0A1V0GSV8 7-105 None
A0A2W4Z4E5 222-344 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.