DPCstruct | MC46516

Metacluster Properties and Pfam Annotations

Number of structural domains96
Mean domain length (aa)330 ± 77 aa
Standard deviation of domain lengths77.45
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score89.18
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.78
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)33.98
Pfam Score100.00
Assigned Pfam label(s) CL0023

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2K6SN73 2-374 GNNAGHTVVVDSVEYDFHLLPSGIINPNVTAFIGNGVVIHLPGLFEEAEKNVQKGKGLEGWEKRLIISDRAHIVFDFHQAADGIQEQ…
A0A845EVE0 7-209 KICVLGNGMVIDPKAFVEEVAYLHERNVSTDNLRISNRAHVILPYHLKLDILQEEEKGVNKIGTTKKGIGPAYMDKAARMGIRIADL…
A0A2A2K597 7-316 None
A0A843E3F9 3-276 None
A0A0J9V3A4 3-244 None
T2RDE1 1-210 None
A0A7F8K8H2 28-400 None
A0A447PVW2 175-359 None
A0A067BY54 54-426 None
M2TI68 503-903 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.