DPCstruct | MC46481

Metacluster Properties and Pfam Annotations

Number of structural domains39
Mean domain length (aa)156 ± 24 aa
Standard deviation of domain lengths24.48
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score73.66
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)40.46
Pfam Score100.00
Assigned Pfam label(s) PF11961

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A446MDC8 108-274 TSKVSRTGSGLGAAGMAGYGRAVEILDTLGCLMTTLSPDGGFISRTTKGTQISILAFEVANTILKGASVMQSLSEDSVTYFKQVVLP…
A0A2P6SKI8 1-146 MVAKLRFPRLMRTRRRKQKAVVGIFAFEVASVMSKLVHLWAFLSSKQVDRLRKKISDSVGIKKLVSHDDDFIRGLIPGELFENMVPL…
A0A4Y7J5I6 131-269 None
A0A7J0GFQ9 128-267 None
A0A1D6EAI4 1-207 None
A0A1B6PQG1 260-420 None
A0A7I4F4L6 78-282 None
A0A6P5MYY5 41-194 None
A0A453T7Z7 22-160 None
A0A6A2XRT8 6-144 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.