DPCstruct | MC46446

Metacluster Properties and Pfam Annotations

Number of structural domains141
Mean domain length (aa)226 ± 60 aa
Standard deviation of domain lengths60.48
Length coefficient of variation0.27
Mean AlphaFold2 pLDDT confidence score86.80
Mean fraction of residues predicted as intrinsically disordered0.34
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)23.78
Pfam Score87.88
Assigned Pfam label(s) PF00557- CL0105- CL0303- PF14374- PF00573

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A836DA99 36-253 SEKAGHQTSAESWGTGRAVARIPRVGGGGTHRSGQAAFGNMCRGGRMFAPTKIWRKWHVKVNQNQRRFAVVSALALLPSLLSSLLVA…
A4H6Q8 69-334 RIVAPVFDLANKVSHTRELDPFIFGLYPETEEMAKNLSYWLVRCQNFSSKWDYENREIWRKAKKNWPNTGMGMARVGDRKNHAHPWG…
A9T3B9 49-263 None
A0A0D8Y2L3 584-808 None
A0A0N4WB61 549-791 None
I2H4P9 38-231 None
A0A7R9W9Q3 1-140 None
A0A0G4MFR5 239-478 None
A0A830CMR5 772-990 None
A0A7Z1LGV0 5-167 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.