DPCstruct | MC46423

Metacluster Properties and Pfam Annotations

Number of structural domains198
Mean domain length (aa)184 ± 27 aa
Standard deviation of domain lengths27.36
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score86.97
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.61
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)16.77
Pfam Score76.34
Assigned Pfam label(s) PF05076- PF12470- PF11979

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2D4IUU6 14-152 EHWHYVSFGLSDLYGDNRVHEFTGSDGPSGFGFELTFRLKRETGESAPPTWPAELMQGLARYVFQSENTFCSGDHVSWHSPLDNSES…
A0A419HZF4 10-185 FLDHVKGYLGPVRETESATTSGVNRGYALFFCAADESGLISVVTNGLRYQPISSRLPQELVCTLRHDQRQAAHHIASATAQVIIEFK…
A0A7S0AMG2 6-180 None
A0A430A7D0 40-240 None
A0A3M1T3Q1 211-421 None
Q08QE5 293-456 None
A0A7J9Z3V3 167-363 None
A0A7W4EY59 75-285 None
L0DB90 121-316 None
A0A7J9Z6J5 16-218 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.