DPCstruct | MC4638

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)116 ± 7 aa
Standard deviation of domain lengths7.14
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score76.90
Mean fraction of residues predicted as intrinsically disordered0.34
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)40.03
Pfam Score100.00
Assigned Pfam label(s) CL0392

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7M5UCU3 35-147 NPDKVDEYTEIFREIQGAYDVLSDRQERAFYDKHREAILRGGDEFVDDSVDLMQYFNPGCHTGHNDTPNGFYAVYGKVFTMVAEEEE…
A0A2C9L0U6 1-117 KNPDNVEEATAQFRLVQQAYEVLSDPQERAWYDKHREAILRGGLGGGDKYDDESLDLFQYFNSTCYSGFGDDDKGFYAVYRKVFETL…
A0A818AX26 464-576 None
A0A1I8H8V6 675-789 None
A0A443RQ14 7-112 None
C1MWB6 40-154 None
A0A7J6SBQ2 40-154 None
A0A167MLU3 54-190 None
A0A1I8IUS1 398-512 None
A0A1I8CHW2 7-119 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.