DPCstruct | MC46366

Metacluster Properties and Pfam Annotations

Number of structural domains361
Mean domain length (aa)179 ± 33 aa
Standard deviation of domain lengths33.11
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score79.36
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.53
Mean intra-cluster sequence similarity (%)15.04
Pfam Score59.83
Assigned Pfam label(s) CL0023- CL0199- CL0402- PF12257- PF06807

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0H5RAM2 15-200 None
A0A832WQM3 2-142 None
A0A0M0JTA0 23-256 None
A0A0M0JQ37 9-168 None
A0A0M0JPL7 131-321 None
A0A1E3QNE4 7-189 None
A0A7J4F2R0 6-176 None
A0A183D3F6 4-179 None
A0A2S2KRZ1 7-246 None
A0A3L7HNS8 26-174 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.