DPCstruct | MC46349

Metacluster Properties and Pfam Annotations

Number of structural domains9
Mean domain length (aa)115 ± 7 aa
Standard deviation of domain lengths7.10
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score93.27
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.93
Mean intra-cluster local Distance Difference Test score0.91
Mean intra-cluster sequence similarity (%)47.43
Pfam Score100.00
Assigned Pfam label(s) PF02769

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A376TU02 39-160 MSMKTRWQEGNEEREMTSPLSLVISAFARVEDVRHTITPQLSTEDNALLLIDLGKGNNALGATALAQVYRQLGDKPADVRDVAQLKG…
A0A855HM69 1-109 MSGVITAFAPVSDVRKTLTPELRQIDGSVLVRIDLSKGQFRIGASILTQVYKAIGTITPDVDSFEDLKDFFNLIQDWNNRGLIQAYH…
A0A377AKY3 1-127 None
A0A8B6ETX4 41-157 None
A0A1E5W079 244-358 None
A0A5P1F8N3 46-155 None
T1HDB2 35-140 None
A0A340X8E8 39-162 None
A0A833KQ63 4-112 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.