DPCstruct | MC46348

Metacluster Properties and Pfam Annotations

Number of structural domains57
Mean domain length (aa)171 ± 31 aa
Standard deviation of domain lengths30.52
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score80.47
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)33.81
Pfam Score88.89
Assigned Pfam label(s) PF07670- PF07664

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A347W3Y8 591-779 FLATFAKENIPNATLASLVGDGIIRGVGAPLSFLPLIATLFLGLTILEGSGYMARVAFLLDGIFVRFGLHGKSFIPLVMGFGCSVPA…
A0A7C1KQE8 63-223 MSADNIFFELFLGKDAGLIQVGITYSIAIILPIVGFFFLSFGIMEDSGYLPRLAVMVNRIFKVIGLNGKAVLPMVMGLGCDTMATLT…
A0A0W1KKQ3 381-572 None
A0A800BR02 1-140 None
A0A1V5JV43 268-381 None
A0A855HM48 259-428 None
A0A0U3NQK7 304-542 None
T0CQK4 99-245 None
A0A117SU15 279-402 None
A0A812NTX6 315-442 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.