DPCstruct | MC46344

Metacluster Properties and Pfam Annotations

Number of structural domains140
Mean domain length (aa)110 ± 14 aa
Standard deviation of domain lengths13.61
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score86.91
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.55
Mean intra-cluster sequence similarity (%)16.50
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A855HKB8 16-122 VPVETITSFKGFDKNLICRNFQYEMGKTYTHDGDVKACGSGFHACEYPLDVLGYYPPSQSRYAVVEQSGDLSREENGDTKVASRSIS…
A0A0K8QRR7 12-124 SADEWCEYHGVKVSRGVATLYKAVNDEWTTSRGVDYSPGSKPACNDFSDTDACGGGLHFGPTPAHALSYFPEATKFVAVGVRVSELR…
A0A0F9GPX7 1-100 None
A0A5P2ERG3 54-153 None
A0A431ID13 12-112 None
A0A388KMR2 178-294 None
A0A5S5CQ68 245-355 None
A0A0G1H4K9 1-100 None
A0A0G4HWX9 101-226 None
A0A3C1GCG9 55-165 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.