DPCstruct | MC4625

Metacluster Properties and Pfam Annotations

Number of structural domains28
Mean domain length (aa)93 ± 7 aa
Standard deviation of domain lengths7.08
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score86.44
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.81
Mean intra-cluster sequence similarity (%)34.49
Pfam Score100.00
Assigned Pfam label(s) PF04712

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2C9KJP4 1-94 TIIKEEERLSSVIAEIDDDVRIIPRGAFIQVPTAEVVKNRSFEGLSVQESAKLCNYMHFREAKRLDLKSLLQRANMDKAIDFMDSIE…
A0A034WVG5 79-167 LKEEERLAAIVFIITEECAVCPRGALYKLTDGRVIPNQMFRGLNDLQVENISNYQILRLPRNDLKHNLLKRSDYNYAIDFLDCIADV…
A0A812UXI1 222-308 None
A0A482SZR5 45-140 None
A0A815BJR6 52-142 None
G0UR23 187-282 None
D2VWI0 84-176 None
A0A7R9JEF0 154-244 None
F0VH91 84-185 None
A0A5A8CDT7 139-231 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.