DPCstruct | MC4619

Metacluster Properties and Pfam Annotations

Number of structural domains8
Mean domain length (aa)198 ± 13 aa
Standard deviation of domain lengths13.04
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score88.06
Mean fraction of residues predicted as intrinsically disordered0.16
Mean length-normalized TM-Score0.84
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)33.20
Pfam Score100.00
Assigned Pfam label(s) CL0286

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
G3B6L6 1-228 MFSKSLKGLLVTAFSALLANAQDITSNTIDRGTISISLGNTHIYPDVYYSIIDVAVASFTGSFNNEGGFYLTSDSSLIALTASIVGT…
Q5AAL9 20-201 AIDITENKVDRGSVTLSFGEIIIHPGASWSIIDNAFSNFIGKLDVKAKSALYISSTSHLLALQVSLTTLLHSINNSGIISFDSRVSL…
A0A421JD66 10-200 None
H2B009 20-206 None
A0A4Y5MUQ8 1-199 None
M3JV22 1-202 None
A0A1A0H1W6 1-201 None
A5DYX2 1-195 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.