DPCstruct | MC46188

Metacluster Properties and Pfam Annotations

Number of structural domains289
Mean domain length (aa)282 ± 72 aa
Standard deviation of domain lengths71.61
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score80.66
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.34
Mean intra-cluster local Distance Difference Test score0.42
Mean intra-cluster sequence similarity (%)12.90
Pfam Score88.10
Assigned Pfam label(s) CL0164- PF04385- PF01016

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
L1LDX7 25-236 ERSPIDLDIAYELPPQICVSISETHPNGRYFYLKKSIANRFRLGLITCADSVIFLGNEKDMLRFVFLQELDDGKRYMRIVSKLADYH…
L1LEB0 6-255 GYSIQITKDQNYGMIYVESVSFGIYVRVTHEHSTSSFFIKSVKYYNHKLVDIKINADTYQKVNVYFWQGEPNRPIMVELINSYSISI…
L1LC01 166-536 None
L1LCV0 8-369 None
L1LCQ7 213-504 None
L1LCM7 266-543 None
L1LCX4 542-1016 None
L1LC00 11-393 None
L1LBJ8 7-272 None
L1LBS6 1-324 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.