DPCstruct | MC46187

Metacluster Properties and Pfam Annotations

Number of structural domains53
Mean domain length (aa)174 ± 29 aa
Standard deviation of domain lengths28.50
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score71.00
Mean fraction of residues predicted as intrinsically disordered0.40
Mean length-normalized TM-Score0.30
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)28.33
Pfam Score100.00
Assigned Pfam label(s) PF06221

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
L0B0S8 22-179 AKKPVKEAPVRNVVKVDSSKSNIPERRRCDCNATEHPLYNNCVGCGRIICTVEGPGDCFQCKRLICPPGTTPPEFSDSQEFSRALFL…
E9ICD8 1-150 RHKCNCEATRHALINNCLNCGRIVCVQEGSGPCFFCEELVCSSKEQALLQSNTKQGDNLYSKLMDQKPSKDFENSLKHRDKLLEFDR…
A0A3L8DUZ2 62-227 None
A0A0N4W5H1 19-175 None
A0A5B8MFN1 125-309 None
A0A1E7FE58 128-291 None
A0A6T7GQ22 178-339 None
A0A7R9AA93 367-501 None
A0A0G4H999 157-313 None
A0A3Q0J8J1 2-167 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.