DPCstruct | MC46143

Metacluster Properties and Pfam Annotations

Number of structural domains101
Mean domain length (aa)102 ± 17 aa
Standard deviation of domain lengths16.76
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score84.40
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.78
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)37.11
Pfam Score100.00
Assigned Pfam label(s) CL0110

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6V7WYH3 18-124 SIFSKPSNSGLPLCPNPPPFLVGPIPTWMDGPNMNKLEQLYSNNVEIGGHGVPKECISRHRVAIIVPYRDREQHLRIFLHNMHSILQ…
A0A158QRM7 2-75 EEIPLKQLEEKFKYLKPGGHYIPNGCKPLNRVAIIIPFRDRESNLHILLNNMHPFLTKQMLDYLIIVVEQVTNQ
A0A1S3ITD2 9-76 None
K1PYH7 19-118 None
A0A4Z2EJQ4 10-96 None
A0A643BY39 48-170 None
A0A1S3J6N6 99-197 None
A0A5N4DAX2 68-191 None
A0A4Y2TFV4 44-146 None
A0A3Q4HUJ8 64-175 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.