DPCstruct | MC461

Metacluster Properties and Pfam Annotations

Number of structural domains13
Mean domain length (aa)414 ± 31 aa
Standard deviation of domain lengths31.29
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score94.36
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.92
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)37.49
Pfam Score100.00
Assigned Pfam label(s) PF06545

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A376W1P5 2-359 KGAVTGALVFEGLAKDLDEAAELAASGEITFSPCHEHDCVGSMAGVTSASMFMHIVKNKTYGNVAYTNMSEQMAKILRMGANDQSVI…
A0A6N7ZVB5 91-522 TIATDSYIRPDKASLLARFQDPACKHVVSEANKEVINRMRQSRPLLVGTGKARDHIPGMKENTVLHAGPPLTWKDANAALRGAIIGG…
A0A7X7IWT6 34-474 None
A0A2V6TAC4 506-976 None
A0A0M0K0G8 610-1061 None
A0A6L8W9M2 177-557 None
A0A354U761 4-401 None
G5LK96 6-413 None
A0A1G9AAJ4 67-486 None
A0A537ABF5 47-429 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.