DPCstruct | MC46074

Metacluster Properties and Pfam Annotations

Number of structural domains50
Mean domain length (aa)186 ± 46 aa
Standard deviation of domain lengths46.06
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score92.57
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.75
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)21.88
Pfam Score92.86
Assigned Pfam label(s) CL0044- PF06243

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7Y3ML00 34-172 NVKLIEQPNGDFAQTILKQYFLSTFNCLLYGALSHSKDETLAAIAAKSLKEVLYHKRHSAEWLKRLGDGTAESKQRMEFALEELWTY…
A0A2V6S2B4 16-198 RHATVMYGLLADLGVDVGGHVSAHDEIFTMRVAADADIGTERITSDKRVNIFYYPIDTWADFIFFNFCMDRGAGHQLEDVRHCSYGP…
A0A6I4KMV3 59-231 None
A0A7W1V013 1-136 None
A0A7Y5G840 2-144 None
A0A838F1X9 23-162 None
A0A7V5RHI9 2-115 None
A0A7V4HDY3 6-131 None
A0A6I1J028 3-127 None
A0A377M302 17-195 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.