DPCstruct | MC46010

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)145 ± 18 aa
Standard deviation of domain lengths18.30
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score77.28
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)28.12
Pfam Score100.00
Assigned Pfam label(s) CL0062

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A645IKZ0 2-123 SNFTKGKISYKMTVVIVCVVGVFQSVMGVEAIIKLAGPFFFACYPIAILLTILGLFKKYVPNEGAYKGSALLVILVSIMESLTVAGV…
T0E3N0 2-140 TTSIGLVSATAQYFTKMSNGKVKYETIVVGVCIFSALVANFGVSAIIKFASPILTVIYPATIVLVLMTLFNNKIKNDNTFKGATYVA…
A0A7Y0N2S9 4-157 None
A0A838WQ31 55-210 None
A0A329EKW4 9-132 None
C2MJF9 8-144 None
A0A850QZ14 1-140 None
A0A7X8K7B7 4-120 None
A0A656SL72 2-151 None
A0A3A1Y2S9 7-141 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.