DPCstruct | MC46003

Metacluster Properties and Pfam Annotations

Number of structural domains23
Mean domain length (aa)83 ± 7 aa
Standard deviation of domain lengths6.57
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score91.26
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.91
Mean intra-cluster local Distance Difference Test score0.87
Mean intra-cluster sequence similarity (%)52.57
Pfam Score87.88
Assigned Pfam label(s) CL0139- CL0063

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
T0CPW1 1-89 MDGLITISSLDEIDVLLTAIVGMIGLVPTLEAIKKGKTIALANKETLVTAGQLVMEEARKRNVDILPVDSEHSAIFQCLNGENKKKL…
A0A2V2EX02 84-151 DVALIAAGGFAGLAYTLRAARLGIKIALANKESLVCGGELVLNAVKKSGSDLVPVDSEHSALFQALSF
A0A7J6U9H5 419-501 None
A0A7V5C3S6 76-156 None
A0A811P1F4 196-278 None
A0A835FZQ5 56-137 None
A0A1Y5IQX7 2-80 None
A0A2Z5QYJ2 108-193 None
A0A6A5L6U5 1047-1126 None
X8B4U2 88-167 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.