DPCstruct | MC46001

Metacluster Properties and Pfam Annotations

Number of structural domains35
Mean domain length (aa)141 ± 14 aa
Standard deviation of domain lengths14.01
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score90.91
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.82
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)28.07
Pfam Score71.98
Assigned Pfam label(s) PF03726- CL0329- PF03725

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
T0CLN1 1-133 MMVEAGAEEIPDELMLEAILFAHEEIKKVVEFVEMIVAEVGKEKIEVTLYKIDEDVEKAVREFATDKMKEAVKTVEKLERMEKMDAV…
A0A099DDG8 3-140 AVLMVESEADLLSEEQMLGAVVFGHDQQQIVIQNINELVKEAGKEKWDWQPEPVNQALNDRIAALAESRMGDAYRITEKQERYAQVD…
A0A447TUR3 3-117 None
A0A1Q7C8B0 174-313 None
A0A843U7B0 217-358 None
A0A7E4SGL6 494-628 None
E2BQX3 81-223 None
X8F8R8 1-165 None
A0A446KY41 25-138 None
A0A024G5H3 230-382 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.