DPCstruct | MC45987

Metacluster Properties and Pfam Annotations

Number of structural domains45
Mean domain length (aa)191 ± 44 aa
Standard deviation of domain lengths43.56
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score77.36
Mean fraction of residues predicted as intrinsically disordered0.36
Mean length-normalized TM-Score0.50
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)27.92
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0M3IQ13 4-174 TKQQHFDLVPPPSENTAEHHRNIDRTSADHYFDDARQISEEEVREALTQEAKRHKYWKGNAAKKMTIEKIQNSVCLHYTLESFTETR…
A0A453AVU0 5-218 DRDVLDEVEIRHLLIEHVGHRCCWGSRPARTWKITSIEDCNVYVGTLETFIEERDTILKKEPYDGGKIDGRDKGPVLGVWELDLRSE…
A0A665TSG9 4-169 None
A0A4Y2CTL4 7-200 None
A0A7R8X7P2 2-214 None
A0A267FVY7 10-259 None
A0A812P5M7 8-149 None
A0A842TKK9 407-593 None
K7FHB5 63-226 None
F1Q936 10-171 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.