DPCstruct | MC4588

Metacluster Properties and Pfam Annotations

Number of structural domains78
Mean domain length (aa)130 ± 23 aa
Standard deviation of domain lengths23.02
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score75.11
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)30.37
Pfam Score98.96
Assigned Pfam label(s) PF10149- PF04194

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Z2CNU3 12-115 DTEVTDLESIAKKVSKEEARFRMFKEAMKSAPDQVIRFQRDGKPIWLSDNPVEVKNCEVCGAERVFEFQVTPQLLCHLKLDTIGELN…
A0A183HSW3 9-123 GDLEDLEDFVDKDMAFKYFNKVVALNPEQVLRYSRGGEPLLATDHAPLAETVPPCSLCGSERQFELQLMPHLLALIGVDDLGKSIDW…
A0A6J1WUZ9 39-190 None
A0A368FNR9 18-141 None
A0A3M6WRQ3 416-577 None
A4RZH5 25-174 None
A0A0B1PLD3 7-100 None
A0A7R9TN02 274-403 None
A0A1R4ABQ2 131-275 None
M2RIV2 121-270 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.