DPCstruct | MC45854

Metacluster Properties and Pfam Annotations

Number of structural domains846
Mean domain length (aa)192 ± 35 aa
Standard deviation of domain lengths34.67
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score87.32
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.44
Mean intra-cluster sequence similarity (%)13.92
Pfam Score87.40
Assigned Pfam label(s) PF18312- CL0707- CL0509- CL0063- PF05226

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2A2K3A5 44-193 None
A0A2A2K4G3 1064-1221 None
A0A2A2K558 19-177 None
A0A5D2D0W4 10-163 None
A2YH33 452-661 None
A0A545V727 132-371 None
A0A5J5S222 517-727 None
A0A6I5VEA9 2-232 None
M3W7F5 3-216 None
A0A518CMN3 2-208 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.