DPCstruct | MC45854

Metacluster Properties and Pfam Annotations

Number of structural domains846
Mean domain length (aa)192 ± 35 aa
Standard deviation of domain lengths34.67
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score87.32
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.44
Mean intra-cluster sequence similarity (%)13.92
Pfam Score87.40
Assigned Pfam label(s) PF18312- CL0707- CL0509- CL0063- PF05226

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7J6M4I4 175-440 None
A4GUE6 2-163 None
A0A844Z9Q6 18-226 None
A0A1B3NC92 124-297 None
A0A1I8B1Q6 495-684 None
A0A715YNQ2 164-337 None
M1BU83 125-283 None
A0A2C9L2P2 15-216 None
E3NB21 555-744 None
A0A2A4TC50 79-258 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.