DPCstruct | MC45854

Metacluster Properties and Pfam Annotations

Number of structural domains846
Mean domain length (aa)192 ± 35 aa
Standard deviation of domain lengths34.67
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score87.32
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.44
Mean intra-cluster sequence similarity (%)13.92
Pfam Score87.40
Assigned Pfam label(s) PF18312- CL0707- CL0509- CL0063- PF05226

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2G9LRC9 343-531 ETLVAGATETTKTNKPKVLMFVMSFCPYGQQMMAVMKPVFELFGDKVDIEPHFVIYGSASYKGKESSYCMGDLCSMHGLYELEEDIR…
A0A0G0PFF4 2-157 VEFSDFECPFCERFFKETLPQIKKEYIDTGKVKLTYRHFPLDFHAAAMPAALASECANEQGKFWEYHDKIFTEQSKISGKTGEIISQ…
A0A1B8F6N8 3-172 None
A0A6L9J0E3 100-295 None
A0A7S8IXZ5 19-206 None
A0A1N7DID2 160-355 None
A0A2W1UQM8 22-224 None
A0A7S4SH30 31-218 None
A0A1D2NCR9 197-417 None
A0A258VQL5 197-391 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.