DPCstruct | MC45800

Metacluster Properties and Pfam Annotations

Number of structural domains79
Mean domain length (aa)242 ± 35 aa
Standard deviation of domain lengths34.84
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score73.80
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.57
Mean intra-cluster local Distance Difference Test score0.53
Mean intra-cluster sequence similarity (%)18.65
Pfam Score97.71
Assigned Pfam label(s) PF14479- PF17046

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3D8Q4F4 607-820 TEHEYIKCYSWIQGIRFSAVFETDFGFSFCKLNAVATHFSRWGTAMGFTSSSSSAPSAEECSEENVRKAKVCLSAINKAFSRAFEDG…
A0A2T6ZSG3 1-220 MESTGVTLGITGLAGLFTTCLQLFDLVSTAKSHGSACQTLLCKLEVEQVFLLKWGEAIGIFNSQGPDHEQRNETYNKRLGDILIRRA…
A0A2V1DBQ1 18-336 None
A0A4Q4W844 56-241 None
A0A2V1D5S8 1-296 None
A0A3N4JAS8 12-230 None
A0A1J9RX25 1-284 None
A0A6G1IYE6 155-521 None
A0A4S9MVC9 10-248 None
A0A4S9NE19 9-224 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.