DPCstruct | MC458

Metacluster Properties and Pfam Annotations

Number of structural domains67
Mean domain length (aa)194 ± 28 aa
Standard deviation of domain lengths28.44
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score84.24
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.55
Mean intra-cluster sequence similarity (%)14.29
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A419EF79 1-173 MNIEYRQEYEPELTAKVRARFADEMNRLRAFGFSDFGCYSELLPNYSLFTHFIIFLLAKANREIIRVESPLRLVMSQPLLVQREQST…
A0A2U8E043 19-238 IGLWLGFQIVRLLSVVRFLGKTKFTGNRITPVAENDTPVWLRELAITQESVLLGEGFVRRHEHTIQLAIHADIPIPCIEYILPGQGV…
A0A525CCG6 7-177 None
A0A4Q2XW45 128-313 None
A0A2V7ST77 3-187 None
A0A517P2E4 50-220 None
A0A517NVV8 407-569 None
A0A3D3NWJ6 53-257 None
A0A6N6Q3C0 32-244 None
A0A517PVL2 15-208 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.