DPCstruct | MC45796

Metacluster Properties and Pfam Annotations

Number of structural domains121
Mean domain length (aa)240 ± 51 aa
Standard deviation of domain lengths50.91
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score83.77
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.60
Mean intra-cluster local Distance Difference Test score0.54
Mean intra-cluster sequence similarity (%)21.94
Pfam Score99.40
Assigned Pfam label(s) PF11719- PF06999

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6D2K0P3 20-236 PEMYSTNIANSITPYGRHVFVHYKTPEAWPFNVEEEGQPQLFAKLLKSRKSELPVQTKLNACEGDGSDGDVLIFPDMVRYKGLKDAD…
A0A2T6ZBZ4 43-307 ITEKCPPSCACSLESLPEDLDIDRVTSLKGTMANYYRHLLVCTGHSDWASKIELDIAEPGGGLAGRIKELTAMRGGGRKDLRDPFSP…
A0A6A4P981 1-211 None
A0A6A4PXZ4 20-229 None
A0A4Y7JEL2 15-222 None
A0A1Y2HE17 103-315 None
A0A0M8N1P3 52-297 None
A0A1E4SM20 14-233 None
A0A061RM99 38-298 None
W4GLP3 26-248 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.