DPCstruct | MC45725

Metacluster Properties and Pfam Annotations

Number of structural domains200
Mean domain length (aa)127 ± 25 aa
Standard deviation of domain lengths25.23
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score69.07
Mean fraction of residues predicted as intrinsically disordered0.55
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)24.25
Pfam Score99.53
Assigned Pfam label(s) CL0123- PF02178

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A183JBQ8 477-612 None
A0A2I4HN88 65-181 None
A0A074ZJS2 2-150 None
A0A074ZKM3 44-169 None
A0A200PU08 81-213 None
I3K528 1-140 None
A0A444UNI8 37-170 None
G0VCC7 3-152 None
B0WTD9 41-203 None
A0A6J2T893 1-211 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.