DPCstruct | MC45679

Metacluster Properties and Pfam Annotations

Number of structural domains4950
Mean domain length (aa)212 ± 53 aa
Standard deviation of domain lengths53.47
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score80.64
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.44
Mean intra-cluster local Distance Difference Test score0.41
Mean intra-cluster sequence similarity (%)13.63
Pfam Score93.75
Assigned Pfam label(s) PF00137- CL0213- CL0221- CL0617- PF03080

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
Q2H0A6 202-504 None
A0A1W1DNX5 4-226 None
A0A377DRH6 6-234 None
A0A0R3TS06 6-183 None
A0A0R3T0A5 3-130 None
W7DQ90 3-158 None
A0A162PAH3 18-184 None
A0A0D3BHJ8 8-229 None
A0A7J9EVK2 132-305 None
A0A7J9E365 156-274 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.