DPCstruct | MC45679

Metacluster Properties and Pfam Annotations

Number of structural domains4950
Mean domain length (aa)212 ± 53 aa
Standard deviation of domain lengths53.47
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score80.64
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.44
Mean intra-cluster local Distance Difference Test score0.41
Mean intra-cluster sequence similarity (%)13.63
Pfam Score93.75
Assigned Pfam label(s) PF00137- CL0213- CL0221- CL0617- PF03080

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
D2W5J5 16-205 None
D2W4D1 2-162 None
A0A4U5NJA6 3-194 None
K0QZ45 24-356 None
A0A1V5XL98 505-718 None
A0A6A6LWF0 130-290 None
A0A2N0RYG9 9-164 None
A0A2I0UCL9 330-528 None
A0A2N0RQ71 76-367 None
A0A2I0UMA7 1-128 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.