DPCstruct | MC45679

Metacluster Properties and Pfam Annotations

Number of structural domains4950
Mean domain length (aa)212 ± 53 aa
Standard deviation of domain lengths53.47
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score80.64
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.44
Mean intra-cluster local Distance Difference Test score0.41
Mean intra-cluster sequence similarity (%)13.63
Pfam Score93.75
Assigned Pfam label(s) PF00137- CL0213- CL0221- CL0617- PF03080

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A392M5Q4 33-181 None
A0A392M4E8 47-216 None
A0A2U1MQU6 169-321 None
A0A2U1MMH3 1-120 None
A0A2U1MGE9 2-179 None
A0A6J8ETH1 313-567 None
A0A2U1MCK9 303-513 None
A0A2U1M3K6 90-286 None
A0A2U1LXX2 79-278 None
A0A2U1LXG7 374-532 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.