DPCstruct | MC45679

Metacluster Properties and Pfam Annotations

Number of structural domains4950
Mean domain length (aa)212 ± 53 aa
Standard deviation of domain lengths53.47
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score80.64
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.44
Mean intra-cluster local Distance Difference Test score0.41
Mean intra-cluster sequence similarity (%)13.63
Pfam Score93.75
Assigned Pfam label(s) PF00137- CL0213- CL0221- CL0617- PF03080

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
S1NEC6 5-228 FCNMNFWKPVYDMKFSEKQEYLVEKVKNEEPVILAINEHASHQTLISNLDKMLGGEYSVVKPNFDNVSHPRSLQNLLIIKDGIKYTI…
A0A7Y5XDP8 132-393 VRVASFNTLNWFTTLDRRGADTAEEQERQLAKLTAALRGLDADVVGLMEVENNGDTAVGAIVDRLNRAAGAGTYTWVRHPYPGTDEI…
A0A821W418 270-457 None
A0A821UG12 2-142 None
A0A4V2EUF6 36-209 None
A0A5N6Q9B3 42-259 None
A0A820EH38 7-151 None
A0A086KED1 463-820 None
A0A1Y2HJG3 498-775 None
A0A2N9IMN5 119-333 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.