DPCstruct | MC45663

Metacluster Properties and Pfam Annotations

Number of structural domains25
Mean domain length (aa)312 ± 46 aa
Standard deviation of domain lengths46.03
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score73.44
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)25.88
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A212CH69 1-315 MVGRNWMCFGSVKIFKSSHLPVGDRFEEPLANLLNEQHCTVKELLEQLKMKKSSAKQQQEVERVKPQREKVHQTLILDPAQRKRLQQ…
A0A834HZZ8 356-646 QLKLKGQPENVTKEPKVVQIQQHQLNILEQQMRQHIQMLTQNFLLTYSVPGFHEKSFQFRDHLMDLKKHADGRDMSVFKQSNLLPAI…
S4RI38 351-659 None
A0A7F8QWR9 1-373 None
T1HBD0 272-495 None
A0A044T8H3 375-629 None
A0A6I9JFY5 23-353 None
B2RCN4 23-264 None
A0A7J6ACD1 1-356 None
A0A060XEF6 537-853 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.