DPCstruct | MC45646

Metacluster Properties and Pfam Annotations

Number of structural domains58
Mean domain length (aa)148 ± 27 aa
Standard deviation of domain lengths27.06
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score77.10
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)28.25
Pfam Score100.00
Assigned Pfam label(s) CL0350

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
K3X992 1-121 MEHESSSTATTSLSATKASKKPSNRKLIQNALEYTLLAGGSMERDRLAALQAMTLSTCENFIVLLKSTRELKFRALYEHHTDRQHVV…
A0A2H1CXY7 209-313 TSGPGVSVAGQPKLFVKPKAKSNRMVIVNAIGHCCLAGAVNEPMKQATLKELASTEGTHFMILFRDSRCQYRAVYAYDLESEELHLI…
V6LLE3 427-599 None
A0A1R2D0S2 21-200 None
A0A1R2CWS7 120-286 None
A2FZI3 616-788 None
B4GZX0 90-205 None
A0A183WHC0 11-114 None
A0A5K3EVV5 593-753 None
C1MII2 853-1015 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.