DPCstruct | MC45629

Metacluster Properties and Pfam Annotations

Number of structural domains13
Mean domain length (aa)259 ± 18 aa
Standard deviation of domain lengths18.39
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score81.30
Mean fraction of residues predicted as intrinsically disordered0.45
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)37.81
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A345RWK1 1-253 MLQRCGFKRNKHNFLYRDDIPAVFKVDDRTPFEFARPGSMQPRLIATEGSTSGMAVSALFSLRTAMGFANEARGLPVSPGGHPNAPQ…
A0A2R7SU20 78-336 LAKAGYRRNKNNCLYRTDVPAMFRGDDRTPFEIARDDTMLPRYRHSPGASTEKPISSTFSLKEGIGYASAPDPEYLLYNSQTNKHPG…
A0A1P8EWI8 407-687 None
A0A7Y9VW73 241-500 None
A0A2U8I392 486-743 None
E0WRM3 176-391 None
A0A5E7Q7J5 338-599 None
A0A4P6GF93 1-237 None
A0A0X1T1X7 432-706 None
A0A2N7XHW1 305-588 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.