DPCstruct | MC45614

Metacluster Properties and Pfam Annotations

Number of structural domains275
Mean domain length (aa)213 ± 44 aa
Standard deviation of domain lengths44.11
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score78.13
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.49
Mean intra-cluster local Distance Difference Test score0.56
Mean intra-cluster sequence similarity (%)17.41
Pfam Score92.44
Assigned Pfam label(s) PF00263- PF03958- CL0159

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A357NED2 32-226 DKSAGSAGRSTDTAGANKEYGSAHLFKTVNVGVAAMLKAKIGKGEGKVLAKPRIIALNSKDAHIHIGRKLPVVEYDKDGNKTVSYIE…
A0A847I3Q6 30-260 AQTLPLSVPIDAQLIILHVQTPRAARDQLNRVWDLVREDSVDSETAVRLYSNGVRMGVGQIARWDAIKDIFDATEKSRVYELPPMVN…
A0A800JC89 13-196 None
A0A2S0PBI7 32-256 None
A0A1Y6B5G5 805-1048 None
A0A800JE71 1-141 None
A0A3E0PKQ7 955-1265 None
A0A7X1AX54 637-855 None
A0A848WSB5 52-270 None
A0A3D1F9Z6 103-354 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.