DPCstruct | MC45595

Metacluster Properties and Pfam Annotations

Number of structural domains19
Mean domain length (aa)216 ± 28 aa
Standard deviation of domain lengths27.68
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score83.74
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)24.48
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A178LZV0 171-358 YDEWNHALATYFTAGIPQGHVVYLSVDDAIIQQIEHQLTVRLGRSPEPFIAAVRRRVVYGQRVVFRRIWGRNRYGEPNCIAFLAAMV…
A0A7Y5T878 7-221 YERWDRALARHIFTEESAGLPVYLEVTPEIFSAVAADLDVPGDPAEHLAKVVRETLYLEDRHGFDAHRERFQMWRRQKLAPTGTLAK…
H8H3M5 1-178 None
A0A6I6G161 2-185 None
A0A2G1UGM3 125-316 None
A0A2D5VJK3 312-534 None
A0A7W4W8W3 6-180 None
A0A4T0V044 8-276 None
T0FSH8 3-252 None
A0A358IRZ6 20-254 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.