DPCstruct | MC45558

Metacluster Properties and Pfam Annotations

Number of structural domains47
Mean domain length (aa)380 ± 69 aa
Standard deviation of domain lengths68.87
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score88.51
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)57.27
Pfam Score96.21
Assigned Pfam label(s) PF00223- CL0029- PF00421- PF05695

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5D2KKH8 71-447 QITFEFFQIWRESGITSELQLYCTAIAALVFAALMLFSGWFQDVESMLNHDLTGLLGLGSLSWAGHQVHRSHFPSFAEGATPFFTLN…
Q1MX23 150-463 GPEGKLAPTGLSFDMFGPITPASMAGNHVAFGAVFFLGGIFHYFAGFNTKKFAFFEKDWEAVLSVSCQVLAFHFATVVFAMIIWQHP…
A0A2J6MDN1 4-469 None
A0A2G2XBU1 4-376 None
A0A7J9KJ29 21-368 None
A0A1R3KZI6 7-314 None
A0A6S7N825 3-322 None
K7X1M8 8-475 None
A0A396I1Z4 1-319 None
A0A2G3CRL2 31-316 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.