DPCstruct | MC45557

Metacluster Properties and Pfam Annotations

Number of structural domains68
Mean domain length (aa)139 ± 26 aa
Standard deviation of domain lengths25.67
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score88.44
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.85
Mean intra-cluster local Distance Difference Test score0.86
Mean intra-cluster sequence similarity (%)64.59
Pfam Score99.00
Assigned Pfam label(s) PF00223- PF00421

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5D2K6U8 1-139 MYKTNWGIGHSLKDILEAHKGPFTGQGHKGLYEILTTSWHAQLSLNLAMLGSLTIVVAHHMYSMPPYPYLATDYGTQLSLFTHHMWI…
A0A2Z2C6A9 135-243 IAGHMYRTNWGIGHGLKDILEAHKGPFTGQGHKGLYEILTTSWHAQLSLNLAMLGSLTIVVAHHMYSMPPYPYLAIDYGTQLSLFTH…
A0A5D2KKH8 200-312 None
A0A5N6P8W7 152-275 None
A0A7J9KJ29 73-246 None
A0A2G3CMI3 3-169 None
A0A1R3KZI6 115-268 None
A0A3B6PKD4 221-353 None
A0A6S7N825 2-175 None
A0A2G2XBU1 215-370 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.