DPCstruct | MC45542

Metacluster Properties and Pfam Annotations

Number of structural domains32
Mean domain length (aa)277 ± 48 aa
Standard deviation of domain lengths48.21
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score88.68
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.77
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)31.62
Pfam Score87.42
Assigned Pfam label(s) CL0004- PF10290

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0L8VMK2 178-495 SYVDVNKFKDITNNESCTCEVGDRVWFSGKNAPLADYLSVHFRGPLKLKQFAFYTSPGFTVNNSRSSSDWNRLAYYESSSKTADNVT…
H0GII3 11-343 QSYQKLDFTNVGFTGSYVDVNKFKDITNNESCTCEVGDRVWFSGKNAPLADYLSVHFRGPLKLKQFAFYTSPGFTVNNSRSSSDWNR…
F7W9A9 107-274 None
F7W9B1 115-306 None
H2AXG7 22-344 None
D0N3P2 185-486 None
A0A024FZY8 376-681 None
A0A371C004 202-445 None
A0A376BAN5 16-290 None
A0A0G2E011 135-403 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.