DPCstruct | MC45500

Metacluster Properties and Pfam Annotations

Number of structural domains638
Mean domain length (aa)116 ± 22 aa
Standard deviation of domain lengths22.33
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score72.57
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)22.00
Pfam Score99.00
Assigned Pfam label(s) CL0123- PF05485- CL0361- CL0219

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6P8VEW0 56-167 TLPDFCAAYGCSNRRSLQTITRGITFHVFPKTEERRRQWEVALRRDGFVSSGRTLLCSEHFRSEDFDRTGQTVRLKDGFVPTVFNFP…
A0A0L0CPP1 3-87 GCRCYFRDCHTNNPKYSRLHFFRFPIKDVERFKKWRQYAKTENMMEFSEMRRKNMNICARHFRAEHFMNYRMDRLTPNAIPTLMR
A0A1Y1N6B5 1-106 None
A0A3Q0IPZ2 72-169 None
A0A3Q0IYL6 166-307 None
A0A7M5WQG4 24-153 None
A0A7M5X5S6 3-131 None
E9FUT2 105-221 None
A0A2B4S595 2-153 None
A0A2B4SCC7 6-120 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.