DPCstruct | MC45490

Metacluster Properties and Pfam Annotations

Number of structural domains104
Mean domain length (aa)85 ± 10 aa
Standard deviation of domain lengths10.14
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score87.03
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.83
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)44.64
Pfam Score100.00
Assigned Pfam label(s) CL0036

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4U1A4E3 23-93 NDGFPVPSRAQAFVRGIIEKIYKKRVAEQIRILYGGSVKPTNVDELMVQPDIDGALVGGASLIAASFGRII
T0TNK2 2-64 CKVVRDVVAADFGQEVADKVRVQYGGSVKPENVAEYMACPDVDGALVGGASLQADSFLALLDF
A0A1Q3DDY8 374-472 None
R7JJV8 280-366 None
A0A4S8ISP0 44-125 None
F3KBR0 2-64 None
A0A2A2K2M1 6-76 None
A0A0D3DTC3 66-144 None
A0A1Z5ST57 556-648 None
A0A7S2V0N5 93-173 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.