DPCstruct | MC45474

Metacluster Properties and Pfam Annotations

Number of structural domains7
Mean domain length (aa)112 ± 3 aa
Standard deviation of domain lengths3.46
Length coefficient of variation0.03
Mean AlphaFold2 pLDDT confidence score79.62
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)39.53
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A376FI40 1-115 MPRQNEEDAARFISLGLKRNQLAVTGSLKFDISVTPELAARAITLRRQWAPRRQVWIATSTHDGEEEIILQAHRKLLEKFPDLLLIL…
A0A5J4DU34 425-533 FSRIEVVLAQNELLAQRFIQLGARRAVAVGNLKIDAPPPPYDNGELEQLRQCLKGRRIFVAASTHPGEDEVVAEAHQKLRADFGDLL…
A0A6L2NF32 1-115 None
A0A3S4I0N6 90-199 None
A0A6A4NRP3 48-152 None
A0A287M0X5 120-232 None
A0A4D8YPN6 123-236 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.