DPCstruct | MC45471

Metacluster Properties and Pfam Annotations

Number of structural domains53
Mean domain length (aa)175 ± 27 aa
Standard deviation of domain lengths27.07
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score77.28
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)33.95
Pfam Score100.00
Assigned Pfam label(s) CL0292

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A376FFI5 24-179 MFIDLFMHRHDKPVSLKSAAMWSIFWVMMAMAFAGFLYVHHGAEMASLFLTGYALEEVLSVDNLFVMMAIFAWFGVPDKYRHRVLYW…
A0A2U1C819 45-199 SVLWFSLSFVFVGLLWWYLNDSQGREVANTVSMQFITGYLVEKSLSIDNIFVFLMIFSYFAVPEQYQKRALIIGIIGAIVLRAILIL…
F8KUW8 23-238 None
A0A7R9TDF4 381-557 None
A0A540K6J5 21-172 None
A0A6V2K595 151-339 None
A0A6G1EHX6 72-244 None
A0A1X6PFB1 94-285 None
A0A7S3ZKM7 7-210 None
A0A0K9QW97 110-256 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.