DPCstruct | MC45404

Metacluster Properties and Pfam Annotations

Number of structural domains1695
Mean domain length (aa)103 ± 16 aa
Standard deviation of domain lengths16.35
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score83.15
Mean fraction of residues predicted as intrinsically disordered0.33
Mean length-normalized TM-Score0.61
Mean intra-cluster local Distance Difference Test score0.58
Mean intra-cluster sequence similarity (%)19.15
Pfam Score90.30
Assigned Pfam label(s) CL0126- PF18265- PF13879- CL0304- CL0466

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1E4ZX87 9-102 SKTSYLGASIEFNEDDMAVISEYTKKGTPAYNAGLEKGDIIIAINNQSFSDIDQFNAALQKHKPGKKVTIMYKRLNVENKVLVKIAP…
A0A2H6ABF1 125-212 WVYPLPENIGLVLEIDAGNRVQRVLPRSPAEQAGLQAGDILVRIHGVPIRSQADCMYALHLAPQQGELTLQFQRGQQLRKAVLCLPYG
A0A7M5US00 201-328 None
A0A7X7ZIV5 386-475 None
A0A168B0M6 457-553 None
A0A518HRC8 260-343 None
A0A349MIK2 71-183 None
A0A165A5R5 411-541 None
A0A139QLU9 33-124 None
A0A837PZJ4 55-161 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.