DPCstruct | MC454

Metacluster Properties and Pfam Annotations

Number of structural domains17
Mean domain length (aa)122 ± 12 aa
Standard deviation of domain lengths11.68
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score66.93
Mean fraction of residues predicted as intrinsically disordered0.89
Mean length-normalized TM-Score0.41
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)46.26
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6A5EAA4 1-97 MSEDNELEKRAVEELLKETDRARVRAETMGPAGWLKCPLQSTNKRFLLNTLRSTGLQRRPSESRDRHPPTRGRRSSESPDRSRDRSR…
A0A6J3EPX3 5-126 EEDPELERKAVEELLKEAKRGRTRAETMGAMGWLKCPLAGANKRFLINTIKNTLPSQKEQDQEREQREVSKEPEPNKSRKEEKPKKR…
A0A401SAH7 65-191 None
A0A674ICQ5 69-184 None
A0A7J8DZ07 22-145 None
A0A6J0YY85 2-118 None
A0A5A9N6I3 3-141 None
A0A2D0PV34 23-138 None
A0A6S7G0F0 7-145 None
A0A835NUG5 40-141 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.